Did you know that oral treatments for erectile dysfunctions are the first line of treatments offered to men who are diagnosed with this condition?
Interestingly they are also the most popular and preferred form of treatment for most men who have to deal with this condition.
There are many different types of medications that are prescribed by the doctors which contain the PDE5 inhibiting drugs which treat erectile dysfunction nowadays. But initially, there was only one PDE5 inhibiting drug that was officially prescribed for the treatment of this condition and it was Viagra. That makes Sildenafil the oldest among the family of the PDE5 inhibiting drugs which also contains Tadalafil and Vardenafil.
Viagra is still synonymous with oral treatments of erection dysfunction so much so that the popular generic brand of Sildenafil citrate Cenforce
is often called as Generic Viagra.
Do all the PDE5 inhibiting drugs treat erectile dysfunction in the same manner?
More or less, yes, all the PDE5 inhibiting drugs prescribed for the treatment of erectile dysfunction have the same working mechanism.
Men who suffer from erectile dysfunction have a specific issue that can be fixed by the PDE5 inhibiting drugs such as Sildenafil citrate, Vardenafil, and Tadalafil.
When men who are suffering from erectile dysfunction sexually aroused or have an urge to have an intimate connection with their partner, then the brain sends the signal to the penile region marking the onset of the production of nitric oxide. In a healthy man, this nitric oxide then widens the blood vessels and directs a flow of blood towards the penis, but it does not go this way for men suffering from erectile dysfunction.
Men suffering from an inability to have erections or stronger erections have the PDE5 enzyme acting in their body which restricts the production of nitric oxide. Due to the inadequate amount the nitric oxide, the blood vessels which line the penile shaft widen to a very less degree or do not widen at all, making the man have weaker or no erections at all.
When a PDE5 inhibiting drug is present and active and present in such a man, it will stop the action the PDE5 enzyme, thus helping in the rise of nitric oxide, when there is enough production of nitric oxide, the blood vessels widen as they should and a man has an erection.
This working mechanism is common among all the PDE5 inhibiting drugs when it comes to bringing about erections.
Which is the best PDE5 inhibiting drug for the treatment of erectile dysfunction?
The best PDE5 inhibiting oral drug for your treatment differs from person to person and various factors come in play for a specific drug to work for an individual.
Sildenafil was the only drug used for everyone suffering from this condition before the discovery and production of Tadalafil and Vardenafil.
The onset period of Sildenafil is 30-60 minutes, while Vardenafil takes about 15-30 minutes the same as that of Tadalafil.
All these drugs are the same in their working, but the formers remain active for 4 hours while the latter remains active for 5 hours. If we base the choice on the amount of time for which the drugs remain active in the body, then Tadalafil is the clear winner here as it remains active in the system for 36 hours and is hugely popular as the weekend treatment of erectile dysfunction.
But we must also consider the fact that the longer the drug stays active in the body, the more likely it is to cause some problems in our body. Sildenafil has a half-life of about 4 hours; Vardenafil takes about 6 hours while Tadalafil takes 17. 5 hours which should make us put some things to the perspective.
People who have a more active sex life can go for Tadalafil, as it can be also used as a daily treatment of erectile dysfunction if prescribed in lower dosages which keeps them ready for action whenever they want.
People who are older or people who make love to their partner occasionally should go for the other do drugs which give a considerable duration to have a successful lovemaking session and get eliminated quickly from the body.
Your doctor will be able to determine the best drug for you after analyzing the severity of your condition, your reaction to certain drugs, medical history, existing medical conditions, and the drugs and medications that you may be using form other diseases and conditions.
Do PDE5 inhibiting drugs increase sexual drive in the man suffering from erectile dysfunction?
None of the PDE5 inhibiting drugs have anything to do with increasing sexual drive or desire. The sexual attraction begins in the brain, and this drug does all its activities around the production of nitric oxide which dilates the blood vessels.
Yes, it is likely erectile dysfunction may have made a man lose confidence in himself and his manhood, which may have decreased his sexual libido. When such a man uses the PDE5 inhibiting drug for his treatment and experiences successful lovemaking sessions, the confidence returns. When a man feels more confident and manly there is a rise in the production of testosterone in his body, which is known to increase a man's sexual drive.
But this can easily happen due to other activities that promote testosterone levels such as a promotion at work, winning at sport, or getting lots of positive attention from the opposite genders.
All the PDE5 inhibiting drugs only inhibit the PDE5 enzyme and aids in nitric oxide production that also only in the presence of prior sexual arousal.
Even when the PDE5 inhibiting drug Sildenafil citrate drug is offered in a union with Dapoxetine in the medication Super P Force
as a combination treatment for premature ejaculation and premature ejaculation, then also all it does is to restrict the PDE5 enzyme and nothing more.
These oral drugs are convenient to use and they are much more affordable than other forms of treatments such as penile injections and surgery. Also, their effects are temporary and they won't be useful if the cause of your erectile dysfunction condition is not the lack of an adequate amount of blood flow in your body.